Isopropyl Myristate (IPM), CAS: 110-27-0

Isopropyl myristate (IPM, CAS 110-27-0) is the isopropyl ester of myristic acid – a colourless to slightly yellow oily liquid used as an emollient, spreading agent and carrier in skin care, colour cosmetics, sun care and topical pharmaceutical formulations. It is a light, non-greasy ester that spreads easily and leaves a dry rather than oily after-feel, which is why it appears in so many cosmetic emulsions.

Specification

Parameter Limit Why it matters
Appearance Colourless or slightly yellow oily liquid Colour is the first visible sign of oxidation or poor refining
Ester content Min 98% The main purity figure – the balance is unreacted alcohol, acid and mono/diglyceride-type by-products
Acid value Max 0.5 mg KOH/g Free fatty acid from incomplete esterification or hydrolysis in storage; also predicts odour and skin-compatibility complaints
Colour (Hazen) Max 30 Colour of the neat ester, which matters in a white or pale formulation
Refractive index (20 deg C) 1.434 – 1.438 Identity check – a chain-length mix-up shows here before it shows anywhere else
Specific gravity (20 deg C) 0.850 – 0.855 Identity and consistency; also used for volume-to-mass conversion in production

What the molecule is

Property Value Practical meaning
Chemical name Isopropyl tetradecanoate (isopropyl myristate) A saturated C14 fatty acid esterified with isopropanol
Formula / molecular weight C17H34O2 / 270.45 Small, highly lipophilic molecule – it penetrates and spreads rather than sitting on the surface
INCI name Isopropyl Myristate The label name used across cosmetic markets
Solubility Insoluble in water; miscible with ethanol, isopropanol, mineral oil and most cosmetic esters Oil-phase ingredient; no emulsifier needed for oil solubility
Polarity Very low Compatible with silicones and hydrocarbons, less so with highly polar oils

Functions in formulation

  • Emollient – softens and smooths the skin surface by filling the spaces between corneocytes, without the heaviness of mineral oil.
  • Spreading agent – lowers the viscosity of the oil phase and helps the product distribute evenly over skin, which is why it appears in sunscreens and body lotions.
  • Penetration enhancer – increases the partitioning of actives into the stratum corneum, a property used deliberately in topical drug delivery.
  • Carrier and diluent – dissolves oil-soluble actives, colourants and UV filters, and adjusts the skin feel of the oil phase.
  • Binder and lubricant – in pressed powders and in some industrial applications.

Typical applications

Sector Use
Skin care Emollient in lotions, creams and body oils; reduces greasiness in rich formulations
Sun care Spreading and solubilising agent for UV filters; improves uniformity of the film
Colour cosmetics Binder and emollient in lipsticks, foundations and pressed powders
Hair care Conditioning ester and lubricant in leave-on products
Topical pharmaceuticals Vehicle and penetration enhancer in creams, gels and transdermal systems
Industrial Lubricant and oil-phase component where a light synthetic ester is wanted

Packaging, storage and documentation

Item Detail
Packaging 175 kg drums and IBC on request; smaller packs available
Storage Sealed, cool, out of direct sunlight. Although IPM is a saturated ester, the acid value rises on prolonged storage – keep containers closed and avoid heat
Documentation Batch COA (ester content, acid value, colour, refractive index, specific gravity) plus SDS and a cosmetic-grade statement
Regulatory Listed cosmetic ingredient; confirm the declaration your market requires before labelling

For the technical background and grade selection, see the isopropyl myristate technical guide and the comparison against other emollient esters.

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