2-Bromo-4-tert-butyl-1-iodobenzene (CAS 860435-39-8) is a functionalised aromatic building block for cross-coupling and nucleophilic substitution, supplied at 97.0% purity as bright yellow powder, with a batch COA and SDS issued against the specification you agree.
Specifications
| Property | Specification |
|---|---|
| Appearance | bright yellow powder |
| Purity | 97.0% |
| CAS number | 860435-39-8 |
| Molecular formula | C10H12BrI |
| Molecular weight | 339.01 g/mol |
| PubChem CID | 44238947 |
| SMILES | CC(C)(C)C1=CC(=C(C=C1)I)Br |
Where it is used
- Orthogonally functionalised aryl halide for sequential cross-coupling.
- Cross-coupling (Buchwald-Hartwig, Suzuki, Sonogashira) at the halogen-bearing position
- Nucleophilic aromatic substitution where the halogen acts as the leaving group
Reading the specification
For aromatic halides, regiochemistry is the specification: the position of the halogen relative to the other substituents decides which site reacts first and how fast, so a positional isomer is a different product, not a grade variant. Two further lines matter: purity by GC, because residual isomeric halide carries through the coupling, and water, which hydrolyses benzylic halides and fouls palladium-catalysed steps.
Packaging and supply
Supplied in research quantities from 1 g and 5 g through 25 g and 100 g, with scale-up to bulk packed under nitrogen or argon where the product allows it. Every lot ships with a batch COA and the current SDS, FOB or CIF against destination. If you need a specific assay method, a water limit, an enantiomeric purity figure or a metal-residue limit, state it at enquiry stage – the batch documentation is issued against the specification you agree.
Handling: Use gloves, eye protection and local ventilation. Avoid dust generation, keep containers closed when not in use, and refer to the SDS for first aid, storage and disposal.
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PolyBlueChem supplies 2-Bromo-4-tert-butyl-1-iodobenzene (CAS 860435-39-8) at 97.0% purity, bright yellow powder, from gram to kilogram scale with per-batch COA and SDS. Send the quantity, the assay method and the purity profile your process needs, and we will confirm the grade and the documentation.
