Dimethyl Sulfate, CAS: 77-78-1

Dimethyl sulfate (DMS, CAS 77-78-1), also known as sulfuric acid dimethyl ester, is a clear and colorless liquid and one of the most important industrial methylating agents, used in pharmaceuticals, agrochemicals, dyes and specialty chemicals.

Specifications

Appearance Clear and colorless liquid
Assay 99.0% min
Acidity 0.3% max
CAS number 77-78-1
Molecular formula C2H6O4S
Molecular weight 126.13 g/mol

Applications

  • Methylating agent for pharmaceutical and agrochemical synthesis.
  • Quaternization of amines for surfactants, textile and personal care chemicals.
  • Methylation in dyes, pigments and fine chemicals.

Handling and Storage

Dimethyl sulfate is a highly toxic and corrosive liquid and a suspected carcinogen. It must be handled in closed systems with strict personal protective equipment, adequate ventilation and immediate access to emergency response procedures. Store in a cool, dry, well-ventilated place away from moisture, alkalis and oxidants, with the container tightly closed.

Chemical Structure

COS(=O)(=O)OC

FAQ

What is dimethyl sulfate used for? It is used mainly as a methylating agent in pharmaceutical, agrochemical, dye and surfactant production.

How should dimethyl sulfate be stored? Keep it cool, dry and tightly sealed, away from moisture and alkalis; handle only with strict safety controls.

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