3-Methoxy-4-methylaniline (CAS 16452-01-0) is a functionalised aromatic building block for cross-coupling and nucleophilic substitution, supplied at 97.0% purity as white solid, with a batch COA and SDS issued against the specification you agree.
Specifications
| Property | Specification |
|---|---|
| Appearance | white solid |
| Purity | 97.0% |
| CAS number | 16452-01-0 |
| Molecular formula | C8H11NO |
| Molecular weight | 137.18 g/mol |
| PubChem CID | 27882 |
| SMILES | CC1=C(C=C(C=C1)N)OC |
Where it is used
- Aniline building block for dyes and active ingredients.
- Cross-coupling (Buchwald-Hartwig, Suzuki, Sonogashira) at the halogen-bearing position
- Nucleophilic aromatic substitution where the halogen acts as the leaving group
Reading the specification
For aromatic halides, regiochemistry is the specification: the position of the halogen relative to the other substituents decides which site reacts first and how fast, so a positional isomer is a different product, not a grade variant. Two further lines matter: purity by GC, because residual isomeric halide carries through the coupling, and water, which hydrolyses benzylic halides and fouls palladium-catalysed steps.
Packaging and supply
Supplied in research quantities from 1 g and 5 g through 25 g and 100 g, with scale-up to bulk packed under nitrogen or argon where the product allows it. Every lot ships with a batch COA and the current SDS, FOB or CIF against destination. If you need a specific assay method, a water limit, an enantiomeric purity figure or a metal-residue limit, state it at enquiry stage – the batch documentation is issued against the specification you agree.
Handling: Use gloves, eye protection and local ventilation. Avoid dust generation, keep containers closed when not in use, and refer to the SDS for first aid, storage and disposal.
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PolyBlueChem supplies 3-Methoxy-4-methylaniline (CAS 16452-01-0) at 97.0% purity, white solid, from gram to kilogram scale with per-batch COA and SDS. Send the quantity, the assay method and the purity profile your process needs, and we will confirm the grade and the documentation.
