Nintedanib (CAS:656247-17-5): Chemical Properties, Manufacturing Processes, Industrial Production, and Pharmaceutical Applications
Abstract Nintedanib (CAS No. 656247-17-5), also known by its development code BIBF 1120, is a highly specialized small-molecule tyrosine kinase inhibitor that has become an important therapeutic agent in the treatment of idiopathic pulmonary fibrosis (IPF), progressive fibrosing interstitial lung diseases, systemic sclerosis-associated interstitial lung disease, and certain forms of non-small cell lung cancer (NSCLC).