β-Nicotinamide adenine dinucleotide phosphate (NADP, CAS 53-59-8) is the phosphorylated pyridine nucleotide coenzyme that serves as the reducing power source in anabolic and P450-dependent reactions. PolyBlueChem supplies NADP free acid as a powder, assay ≥98%, biotransformation grade, with per-batch COA and SDS.
Specifications
| Property | Specification |
|---|---|
| Product form | Powder (free acid) |
| Assay | 98.0% min |
| Grade | Biotransformation grade |
| Appearance | White to slightly yellow powder |
| Water content | Confirmed per batch on the COA |
| Solubility | Soluble in water; dissolves more slowly than the sodium salts – convert to a salt where full solubility is required |
| Storage | -20 °C, sealed, protected from light and moisture |
Free acid or sodium salt? Choose by sodium load
| Form | CAS | Sodium per mole | When to choose it |
|---|---|---|---|
| NADP free acid (this product) | 53-59-8 | 0 | Reference standards, stock solutions you will titrate to pH yourself, and systems where sodium must be minimised |
| NADP monosodium (NADP-Na) | 1184-16-3 | 1 | Low-sodium enzyme systems that still need a soluble salt |
| NADP disodium (NADP-Na2) | 24292-60-2 | 2 | Standard form for biocatalysis; also available as a 75% min aqueous solution |
| NADPH tetrasodium | 2646-71-1 | 4 | The reduced coenzyme, for NADPH-dependent enzyme reactions |
Basic Information
| CAS number | 53-59-8 |
| Chemical name | β-Nicotinamide adenine dinucleotide phosphate (NADP, NADP+, triphosphopyridine nucleotide) |
| Formula / MW | C21H28N7O17P3 / 743.4 g/mol |
| PubChem CID | 5885 |
| Type | Pyridine nucleotide coenzyme, phosphorylated, oxidised form |
Applications
- Biocatalysis – precursor of the NADPH pool in cell-free reductions; paired with glucose-6-phosphate/G6PDH, phosphite dehydrogenase or isopropanol/alcohol dehydrogenase regeneration systems.
- Enzymatic analysis – assay buffers and calibration standards for NADP(H)-dependent dehydrogenases.
- Research – NADP+ biochemistry, glutathione metabolism and oxidative-stress studies.
Supplied as a biochemical reagent; not offered for therapeutic or supplement claims.
Handling, storage and documentation
- Hygroscopic powder – equilibrate to room temperature before opening and reseal promptly.
- Hydrolyses in strongly acidic or alkaline media; keep solutions near neutral pH and protect from light.
- Per-batch COA and SDS supplied; assay method statement available on request.
- Packaging agreed against the required quantity, from laboratory packs to bulk.
Related products
- NADP monosodium salt (CAS 1184-16-3) – one sodium per mole
- NADP disodium salt (CAS 24292-60-2) – 75% min solution and 98% min powder
- NADPH free acid (CAS 53-57-6) – reduced form
- NADH disodium salt (CAS 606-68-8) – reduced form, assay 98% min
- NAD (CAS 53-84-9) – 85% min solution, 98% min and 99% min powders
Further reading
- NADP free acid, monosodium or disodium: choosing the salt form
- NAD, NADH, NADP and NADPH: coenzyme forms, salt types and bulk supply
PolyBlueChem supplies β-NADP free acid (CAS 53-59-8), assay 98.0% min, biotransformation grade, with per-batch COA and SDS and FOB/CIF delivery. Contact us with your quantity, salt-form preference and destination.
