β-Nicotinamide adenine dinucleotide phosphate, monosodium salt (NADP-Na, CAS 1184-16-3) is the mono-sodium form of the phosphorylated pyridine nucleotide coenzyme. PolyBlueChem supplies NADP sodium salt as a powder, assay ≥98%, biotransformation grade, with per-batch COA and SDS.
Specifications
| Property | Specification |
|---|---|
| Product form | Powder |
| Assay (HPLC) | 98.0% min |
| Grade | Biotransformation grade |
| Appearance | White to slightly yellow powder |
| Water content | Confirmed per batch on the COA (hygroscopic) |
| Solubility | Freely soluble in water and aqueous buffer |
| Storage | -20 °C, sealed, protected from light and moisture |
Monosodium or disodium? A buyer’s decision table
| Criterion | NADP-Na (this product) | NADP-Na2 (24292-60-2) |
|---|---|---|
| Sodium per mole of coenzyme | 1 | 2 |
| Effect on reaction ionic strength | Lower – preferred when the buffer is already high salt | Higher – check the conductivity of the final mix |
| Enzyme sensitivity to Na+ | Better where the enzyme is inhibited above a sodium threshold | Standard commercial form; most protocols are written against it |
| Solubility in water | Good | Good (marginally higher) |
| Typical use | Enzyme systems with tight ionic-strength control; analytical work | General biocatalysis and regeneration systems |
Both forms carry the same coenzyme activity per mole; the difference is the counter-ion load. If your protocol quotes a concentration in mg/mL, convert on a molar basis before substituting one salt for the other.
Basic Information
| CAS number | 1184-16-3 |
| Chemical name | β-Nicotinamide adenine dinucleotide phosphate, monosodium salt (NADP-Na) |
| Formula / MW | C21H27N7NaO17P3 / 765.4 g/mol (anhydrous basis) |
| PubChem CID | 5702267 |
| Type | Pyridine nucleotide coenzyme, phosphorylated, oxidised form |
Applications
- Biocatalysis – NADPH-dependent oxidoreductase reactions where the sodium contribution of the disodium salt would disturb the ionic balance (high-salt buffers, cell-free systems with sensitive coupling enzymes).
- Enzymatic analysis – preparation of calibration standards and assay buffers.
- Research – NADP+ biochemistry and redox enzymology.
Supplied as a biochemical reagent; not offered for therapeutic claims.
Handling, storage and documentation
- Hygroscopic – equilibrate the container to room temperature before opening, and reseal immediately.
- Prepare solutions near neutral pH; NADP hydrolyses in strongly acidic or alkaline media.
- Per-batch COA and SDS supplied; assay method statement available on request.
- Packaging agreed against the required quantity, from laboratory packs to bulk drums.
Related products
- NADP free acid (CAS 53-59-8) – assay 98% min
- NADP disodium salt (CAS 24292-60-2) – 75% min solution and 98% min powder
- NADPH tetrasodium salt (CAS 2646-71-1) – assay 95% min
- NADH disodium salt (CAS 606-68-8) – reduced form, assay 98% min
- NAD (CAS 53-84-9) – 85% min solution, 98% min and 99% min powders
Further reading
- NADP free acid, monosodium or disodium: choosing the salt form
- Coenzyme bulk buying: assay basis, documentation and cold chain
- NAD, NADH, NADP and NADPH: coenzyme forms, salt types and bulk supply
PolyBlueChem supplies β-NADP monosodium salt (CAS 1184-16-3), assay 98.0% min, biotransformation grade, with per-batch COA and SDS and FOB/CIF delivery. Contact us with your quantity, salt form and destination.
